Browsing by Author "Ogutu, Bernhards"

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Development, characterization and antimalarial efficacy of dihydroartemisinin loaded solid lipid nanoparticles

Omwoyo, Wesley N.; Paula, Melariri; Gathirwa, Jeremiah W.; Oloo, Florence; Mahanga, Geoffrey M.; Kalombo, Lonji; Ogutu, Bernhards; Hulda, Swai (Science direct, 2016-04)

Effective use of dihydroartemisinin (DHA) is limited by poor water-solubility, poor pharmacokinetic profile and unsatisfactory clinical outcome especially in monotherapy. To reduce such limitations, we reformulated DHA ...
Preparation, characterization, and optimization of primaquine-loaded solid lipid nanoparticles

Omwoyo, Wesley Nyaigoti; Ogutu, Bernhards; Oloo, Florence (Dove Press, 2014-08)

Primaquine (PQ) is one of the most widely used antimalarial drugs and is the only available drug that combats the relapsing form of malaria. PQ use in higher doses is limited by severe tissue toxicity including hematological- ...
Preparation, characterization, and optimization of primaquine-loaded solid lipid nanoparticles

Omwoyo, Wesley Nyaigoti; Ogutu, Bernhards; Oloo, Florence; swai, hulda; Kalombo, lonji; Melariri, Paula; Mahanga, geoffrey Maroa; Waweru, Jeremiah; gathirwa (2014)

Primaquine (PQ) is one of the most widely used antimalarial drugs and is the only available drug that combats the relapsing form of malaria. PQ use in higher doses is limited by severe tissue toxicity including hematological- ...

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